Dicyclohexylcarbodiimide → 2-Dimethylaminopyridine

HRID 235211

Reaction equation

HRID 235211 reaction equation
[CH3:1][C@H]1OC(=O)C2C(O)=CC(O)=C(Cl)C=2CC(=O)C=CC=C[C@H]2O[C@H]2C1.C(OC(NCCCCCCCCCCCC(O)=O)=O)C=C.[CH:47]1([N:53]=[C:54]=[N:55][CH:56]2[CH2:61][CH2:60][CH2:59]CC2)CCCCC1>CN1CCCC1=O>[CH3:1][N:53]([C:54]1[CH:59]=[CH:60][CH:61]=[CH:56][N:55]=1)[CH3:47]

Participants

5

Reactant 3

HCID 10868DicyclohexylcarbodiimideHCID 11268547CID 11268547HCID 1165233712-{[(Prop-2-en-1-yloxy)carbonyl]amino}dodecanoic acid

Product 1

HCID 218852-Dimethylaminopyridine

Reagents, catalysts & solvents 1

HCID 13387N-methyl-2-pyrrolidoneSolvent

Procedure

Following a procedure similar to that described in Example 12, but using 547 mg of radicicol, 3.75 g of 12-allyloxycarbonylaminododecanoic acid, 15 ml of dry 1-methyl-2-pyrrolidinone, 1.6 g of dicyclohexylcarbodiimide and a catalytic amount of dimethylaminopyridine, 418 mg of the title compound were obtained.

Sources & evidence

ORD record
ord-0d49396f87aa4d0694bd0c6068091e57
Source dataset
uspto-grants-1997_01
Patent number
US05597846

Linked notes

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