Dicyclohexylcarbodiimide → 2-Dimethylaminopyridine

HRID 235212

Reaction equation

HRID 235212 reaction equation
[CH3:1][C@H]1OC(=O)C2C(O)=CC(O)=C(Cl)C=2CC(=O)C=CC=C[C@H]2O[C@H]2C1.C(O)(=O)CCCCCCCCCCCCCC.[CH:43]1([N:49]=[C:50]=[N:51][CH:52]2[CH2:57][CH2:56][CH2:55]CC2)CCCCC1>O1CCCC1>[CH3:1][N:49]([C:50]1[CH:55]=[CH:56][CH:57]=[CH:52][N:51]=1)[CH3:43]

Participants

5

Reactant 3

HCID 10868DicyclohexylcarbodiimideHCID 13849Pentadecanoic AcidHCID 11268547CID 11268547

Product 1

HCID 218852-Dimethylaminopyridine

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

Following a procedure similar to that described in Example 12, but using 500 mg of radicicol, 830 mg of pentadecanoic acid, 15 ml of dry tetrahydrofuran, 707 mg of dicyclohexylcarbodiimide and a catalytic amount of dimethylaminopyridine, 782 mg of the title compound were obtained.

Sources & evidence

ORD record
ord-6638c1d13ecf416d8f33623e10da7a25
Source dataset
uspto-grants-1997_01
Patent number
US05597846

Linked notes

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