Hydrochloric Acid → HCID 69078069, compound
Reaction equation
[ClH:1].[CH3:2][O:3][C:4]1[CH:5]=[C:6](/[C:12](=[CH:15]/[C:16]2[O:17][C:18]([N:21]3[CH2:26][CH2:25][N:24]([CH3:27])[CH2:23][CH2:22]3)=[CH:19][CH:20]=2)/[C:13]#[N:14])[CH:7]=[CH:8][C:9]=1[O:10][CH3:11]>>[ClH:1].[CH3:2][O:3][C:4]1[CH:5]=[C:6](/[C:12](=[CH:15]/[C:16]2[O:17][C:18]([N:21]3[CH2:26][CH2:25][N:24]([CH3:27])[CH2:23][CH2:22]3)=[CH:19][CH:20]=2)/[C:13]#[N:14])[CH:7]=[CH:8][C:9]=1[O:10][CH3:11]Participants
3
Procedure
0.1N Hydrochloric acid (3.1 mL) was added to Compound 27 (100 mg) for dissolution, and purified water (5 mL) was added to the solution, followed by stirring at room temperature for 30 minutes. The reaction mixture was lyophilized, to thereby yield the target product (yield: 109 mg, 99%).
Workup
- custompurified water (5 mL)
- additionwas added to the solution
Sources & evidence
- ORD record
- ord-65c071fe49e343d0b94941a96b5b4fee