Ethyl Acetate → (S)-4-Amino-N-((3-fluoro-4-(trifluoromethoxy)phenyl)(3-fluoropyridin-2-yl)methyl)-5-methoxypicolinamide
Reaction equation
[F:1][C:2]1[CH:3]=[C:4]([C@@H:13]([C:28]2[C:33]([F:34])=[CH:32][CH:31]=[CH:30][N:29]=2)[NH:14][C:15](=[O:27])[C:16]2[CH:21]=[C:20]([N+:22]([O-])=O)[C:19]([O:25][CH3:26])=[CH:18][N:17]=2)[CH:5]=[CH:6][C:7]=1[O:8][C:9]([F:12])([F:11])[F:10].CCOC(C)=O>[Ni].CO>[NH2:22][C:20]1[C:19]([O:25][CH3:26])=[CH:18][N:17]=[C:16]([C:15]([NH:14][C@@H:13]([C:4]2[CH:5]=[CH:6][C:7]([O:8][C:9]([F:10])([F:11])[F:12])=[C:2]([F:1])[CH:3]=2)[C:28]2[C:33]([F:34])=[CH:32][CH:31]=[CH:30][N:29]=2)=[O:27])[CH:21]=1Participants
5
