Hydrochloric Acid → (R)-3-[2-(3-hydroxypyrrolidin-1-yl)ethyl]-5-methyl-2H-isoquinolin-1-one hydrochloride
Reaction equation
[OH:1][C@@H:2]1[CH2:6][CH2:5][N:4]([CH2:7][CH2:8][C:9]2[NH:10][C:11](=[O:20])[C:12]3[C:17]([CH:18]=2)=[C:16]([CH3:19])[CH:15]=[CH:14][CH:13]=3)[CH2:3]1.[ClH:21]>>[ClH:21].[OH:1][C@@H:2]1[CH2:6][CH2:5][N:4]([CH2:7][CH2:8][C:9]2[NH:10][C:11](=[O:20])[C:12]3[C:17]([CH:18]=2)=[C:16]([CH3:19])[CH:15]=[CH:14][CH:13]=3)[CH2:3]1Participants
3
Procedure
Using a known method, (R)-3-[2-(3-hydroxypyrrolidin-1-yl)ethyl]-5-methyl-2H-isoquinolin-1-one was converted to a hydrochloride to give (R)-3-[2-(3-hydroxypyrrolidin-1-yl)ethyl]-5-methyl-2H-isoquinolin-1-one hydrochloride.
Sources & evidence
- ORD record
- ord-e76e3a73302b450e9c1c266deb852e3a
- Source dataset
- uspto-grants-2008_12