5-Chlorovaleryl chloride → 5-Chloro-1-(2,3-dihydro-2,2-dimethyl-1-benzofuran-5-yl)pentane-1-one

HRID 2374610Notes

Reaction equation

HRID 2374610 reaction equation
[CH3:1][C:2]1([CH3:11])[CH2:6][C:5]2[CH:7]=[CH:8][CH:9]=[CH:10][C:4]=2[O:3]1.[Cl:12][CH2:13][CH2:14][CH2:15][CH2:16][C:17](Cl)=[O:18]>>[Cl:12][CH2:13][CH2:14][CH2:15][CH2:16][C:17]([C:8]1[CH:9]=[CH:10][C:4]2[O:3][C:2]([CH3:11])([CH3:1])[CH2:6][C:5]=2[CH:7]=1)=[O:18]

Participants

3

Reactant 2

HCID 740895-Chlorovaleryl chlorideHCID 806402,3-Dihydro-2,2-dimethylbenzofuran

Product 1

HCID 218875485-Chloro-1-(2,3-dihydro-2,2-dimethyl-1-benzofuran-5-yl)pentane-1-one

Procedure

Using 2,2-dimethyl-2,3-dihydro-1-benzofuran (3.0 g) and 5-chlorovaleryl chloride (3.4 g) according to the same method as that of Reference Example 1, the title compound was obtained as a fine yellow oil (3.6 g).

Sources & evidence

ORD record
ord-461b2564eff840858fd17b902853e732
Source dataset
uspto-grants-2008_12
Patent number
US07462628B2

Reaction notes

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