Ethylenediamine → N~1~-(Pyridin-2-yl)ethane-1,2-diamine

HRID 238498

Reaction equation

HRID 238498 reaction equation
[CH2:1]([NH2:4])[CH2:2][NH2:3].F[C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][N:7]=1>>[N:7]1[CH:8]=[CH:9][CH:10]=[CH:11][C:6]=1[NH:3][CH2:2][CH2:1][NH2:4]

Participants

3

Reactant 2

HCID 3301EthylenediamineHCID 97462-Fluoropyridine

Product 1

HCID 410428N~1~-(Pyridin-2-yl)ethane-1,2-diamine

Procedure

Ethylenediamine (6 g, 0.1 mol) and 2-fluoropyridine (10 g, 0.1 mol) were heated neat at 120° C. overnight. The reaction was cooled and the residue was used in next step without further purification.

Workup

  1. temperatureThe reaction was cooled
  2. customthe residue was used in next step without further purification

Sources & evidence

ORD record
ord-d13c71bd5af9458eb262afc0d4dc0739
Source dataset
uspto-grants-2014_02
Patent number
US08642624B2

Linked notes

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