Dimethylamine, hydrochloride → 1-Cyclo-hexyl-6-[(5-((N,N-dimethylamino)carbonyl)pentyl)oxy]-2-phenyl-benzimidazole

HRID 23893

Reaction equation

HRID 23893 reaction equation
[CH:1]1([N:7]2[C:11]3[CH:12]=[C:13]([O:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][C:22]([O:24]C)=O)[CH:14]=[CH:15][C:10]=3[N:9]=[C:8]2[C:26]2[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.Cl.[CH3:33][NH:34][CH3:35]>>[CH:1]1([N:7]2[C:11]3[CH:12]=[C:13]([O:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][C:22]([N:34]([CH3:35])[CH3:33])=[O:24])[CH:14]=[CH:15][C:10]=3[N:9]=[C:8]2[C:26]2[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 10473Dimethylamine, hydrochlorideHCID 101591401-Cyclohexyl-6-[(5-(methoxycarbonyl)pentyl)oxy]-2-phenyl-benzimidazole

Product 1

HCID 101600001-Cyclo-hexyl-6-[(5-((N,N-dimethylamino)carbonyl)pentyl)oxy]-2-phenyl-benzimidazole

Procedure

1-Cyclohexyl-6-[(5-(methoxycarbonyl)pentyl)oxy]-2-phenyl-benzimidazole is reacted according to general operating instructions 7 with dimethylamine hydrochloride. 1-Cyclo-hexyl-6-[(5-((N,N-dimethylamino)carbonyl)pentyl)oxy]-2-phenyl-benzimidazole is obtained as a solid.

Sources & evidence

ORD record
ord-98597e0ea363487895c82dcfa80df060
Source dataset
uspto-grants-2005_02
Patent number
US06855714B2

Linked notes

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