Benzylamine → N-(1,1-Dimethoxypropan-2-ylidene)-1-phenylmethanamine

HRID 239125

Reaction equation

HRID 239125 reaction equation
[CH3:1][O:2][CH:3]([O:7][CH3:8])[C:4]([CH3:6])=O.S([O-])([O-])(=O)=O.[Mg+2].[CH2:15]([NH2:22])[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1>>[CH2:15]([N:22]=[C:4]([CH3:6])[CH:3]([O:7][CH3:8])[O:2][CH3:1])[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1

Participants

4

Reactant 3

HCID 7504BenzylamineHCID 24083Sulfuric acid magnesium salt (1:1)HCID 80650Pyruvic aldehyde dimethyl acetal

Product 1

HCID 71380533N-(1,1-Dimethoxypropan-2-ylidene)-1-phenylmethanamine

Procedure

12.9 mL 1,1-dimethoxyacetone was added to 10 mL benzylamine in 100 mL petrolether. Magnesiumsulfate was added and the reaction was stirred over night at RT. The mixture was filtered and evaporated to give 18.9 g of the desired product. (M+H)+: 209

Workup

  1. filtrationThe mixture was filtered
  2. customevaporated

Sources & evidence

ORD record
ord-b3bc05dd952240c8a50ff875b993000c
Source dataset
uspto-grants-2014_02
Patent number
US08642774B2

Linked notes

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