HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2,4-Dioxo-1,3-thiazolidin-3-yl)acetic acid → [(5Z)-5-({1-[4-Chloro-2-(trifluoromethyl)benzyl]-3-(4-fluorophenyl)-1H-indazol-5-yl}methylidene)-2,4-dioxo-1,3-thiazolidin-3-yl]acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2,4-Dioxo-1,3-thiazolidin-3-yl)acetic acid | HCID 2770836 | — |
| Reactant | 1-(4-chloro-2-trifluoromethylbenzyl)-3-(4-fluorophenyl)-1H-indazole-5-carbaldehyde | HCID 86659710 | — |
| Product | [(5Z)-5-({1-[4-Chloro-2-(trifluoromethyl)benzyl]-3-(4-fluorophenyl)-1H-indazol-5-yl}methylidene)-2,4-dioxo-1,3-thiazolidin-3-yl]acetic acid | HCID 58530686 | — |
Reaction Steps
[(5Z)-5-({1-[4-Chloro-2-(trifluoromethyl)benzyl]-3-(4-fluorophenyl)-1H-indazol-5-yl}methylidene)-2,4-dioxo-1,3-thiazolidin-3-yl]acetic acid was prepared from 1-(4-chloro-2-trifluoromethylbenzyl)-3-(4-fluorophenyl)-1H-indazole-5-carbaldehyde and (2,4-dioxothiazolidin-3-yl)acetic acid following General Procedure F.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08796256B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-715284b356914ce3b5747d6e7de83fde |
| Source note | uspto-grants-2014_08 |