Ethanol → Ethyl bis(pentafluoroethyl)phosphinite
Reaction equation
[F:1][C:2]([P:8](Cl)[C:9]([F:15])([F:14])[C:10]([F:13])([F:12])[F:11])([F:7])[C:3]([F:6])([F:5])[F:4].[CH2:17]([OH:19])[CH3:18]>CN(C)C1C=CN=CC=1.C(OCC)C>[F:1][C:2]([P:8]([C:9]([F:15])([F:14])[C:10]([F:13])([F:12])[F:11])[O:19][CH2:17][CH3:18])([F:7])[C:3]([F:6])([F:5])[F:4]Participants
5
Reactant 2
Product 1
Reagents, catalysts & solvents 2
Procedure
Bis(pentafluoroethyl)phosphinous acid chloride, (C2F5)2PCl, obtainable in accordance with Example 2, is added to a mixture of ethanol and 4-dimethylaminopyridine in diethyl ether at room temperature. The precipitated product 4-dimethylaminopyridinium chloride is separated off, and the solution comprises ethyl bis(pentafluoroethyl)phosphinite, (C2F5)2POC2H5.
Workup
- customThe precipitated product 4-dimethylaminopyridinium chloride is separated off
Sources & evidence
- ORD record
- ord-eda27c680cc84ed38fcae7051d4ad4c6
- Source dataset
- uspto-grants-2014_02
- Patent number
- US08648202B2
Reaction notes
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