Hydroxyamine hydrochloride → HCID 73181603, compound
Reaction equation
[Cl:1][C:2]1[C:11]([CH:12]=O)=[CH:10][C:9]2[C:4](=[CH:5][C:6]([O:16][CH3:17])=[C:7]([O:14][CH3:15])[CH:8]=2)[N:3]=1.Cl.[NH2:19][OH:20]>N1C=CC=CC=1>[Cl:1][C:2]1[C:11]([CH:12]=[N:19][OH:20])=[CH:10][C:9]2[C:4](=[CH:5][C:6]([O:16][CH3:17])=[C:7]([O:14][CH3:15])[CH:8]=2)[N:3]=1Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
To 50 g of 2-chloro-6,7-dimethoxy-3-quinolinecarboxaldehyde was added 50 g of hydroxylamine hydrochloride in 500 ml of pyridine. The mixture was stirred at room temperature for 16 hours and the solvent was then evaporated to leave a semi-solid material. This was washed with water, filtered and recrystallized from dimethylformamide to give 2-chloro-6,7-dimethoxy-3-quinolinecarboxaldehyde oxime melting at about 237°-237.5° C. with decomposition.