2-Amino-2-methyl-1,3-propanediol → HCID 54052581, compound

HRID 2413573

Reaction equation

HRID 2413573 reaction equation
[CH3:1][S:2]([O:5][CH2:6][C:7]([NH:11][CH2:12][C:13]1[CH:14]=C2C(=C3[C:30]=1C=CC=C3)C=CC1C=CC=CC2=1)([CH3:10])[CH2:8][OH:9])(=[O:4])=[O:3].C1[C:48]2[CH:47]=[CH:46][C:45]3[C:36](=[CH:37]C=[C:39]4[C:44]=3[CH:43]=[CH:42][CH:41]=[CH:40]4)[C:35]=2[CH:34]=CC=1C=O.N[C:52](C)(CO)CO>CCO>[CH3:1][S:2]([O:5][CH2:6][C:7]([NH:11][CH2:12][C:13]1[CH:30]=[CH:34][C:35]2[C:36]3[C:45](=[C:44]4[C:39](=[CH:52][CH:37]=3)[CH:40]=[CH:41][CH:42]=[CH:43]4)[CH:46]=[CH:47][C:48]=2[CH:14]=1)([CH3:10])[CH2:8][OH:9])(=[O:4])=[O:3]

Participants

5

Reactant 3

HCID 15312-Amino-2-methyl-1,3-propanediolHCID 15599322Chrysene-2-carbaldehydeHCID 540960872-((6-Chrysenylmethyl)amino)-2-methyl-1,3-propanediol methanesulfonate

Product 1

HCID 54052581HCID 54052581, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Using the reductive amination procedure outlined in 1C, chrysene-2-carbaldehyde (20D) and 2-amino-2-methyl-1,3-propanediol (Aldrich) gave 2-((2-chrysenylmethyl)amino)-2-methyl-1,3-propanediol methanesulfonate, mp 225°-227° (dec), (abs. EtOH), (C, H, N, S)

Sources & evidence

ORD record
ord-26d51dc902e640c5921dda0a3e3876b5
Source dataset
uspto-grants-1988_01
Patent number
US04719046

Linked notes

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