2-Amino-2-methyl-1,3-propanediol → 2-((4,5-Dichloro-9-anthracenylmethyl)amino)-2-methyl-1,3-propanediol hydrochloride

HRID 2413633

Reaction equation

HRID 2413633 reaction equation
[Cl:1][C:2]1[C:15]2[C:6](=[C:7]([CH:17]=O)[C:8]3[C:13]([CH:14]=2)=[C:12]([Cl:16])[CH:11]=[CH:10][CH:9]=3)[CH:5]=[CH:4][CH:3]=1.[NH2:19][C:20]([CH3:25])([CH2:23][OH:24])[CH2:21][OH:22]>>[ClH:1].[Cl:1][C:2]1[C:15]2[C:6](=[C:7]([CH2:17][NH:19][C:20]([CH3:25])([CH2:23][OH:24])[CH2:21][OH:22])[C:8]3[C:13]([CH:14]=2)=[C:12]([Cl:16])[CH:11]=[CH:10][CH:9]=3)[CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 15312-Amino-2-methyl-1,3-propanediolHCID 6007414,5-Dichloro-9-anthraldehyde

Product 1

HCID 133753012-((4,5-Dichloro-9-anthracenylmethyl)amino)-2-methyl-1,3-propanediol hydrochloride

Procedure

Using the reductive amination procedure outlined in 1, 4,5-dichloro-9-anthracenecarbaldehyde (10A) and 2-amino-2-methyl-1,3-propanediol (Aldrich) gave 2-(((4,5-dichloro-9-anthracenyl)methyl)amino)-2-methyl-1,3-propanediol hydrochloride mp 239.5°-240.5° (dec), (EtOH/Et2O), (C, H, Cl, N). l

Sources & evidence

ORD record
ord-3e67357ad7164a2483095423312f6366
Source dataset
uspto-grants-1988_01
Patent number
US04719049

Linked notes

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