Hydrochloric Acid → 2-Amino-2'-[alpha-(hydroxyimino)benzyl]-4'-nitro-acetanilide hydrochloride

HRID 2418316

Reaction equation

HRID 2418316 reaction equation
[ClH:1].[NH2:2][CH2:3][C:4]([NH:6][C:7]1[CH:12]=[CH:11][C:10]([N+:13]([O-:15])=[O:14])=[CH:9][C:8]=1[C:16](=[N:23][OH:24])[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1)=[O:5]>C(Cl)Cl.C(O)C>[ClH:1].[NH2:2][CH2:3][C:4]([NH:6][C:7]1[CH:12]=[CH:11][C:10]([N+:13]([O-:15])=[O:14])=[CH:9][C:8]=1[C:16](=[N:23][OH:24])[C:17]1[CH:18]=[CH:19][CH:20]=[CH:21][CH:22]=1)=[O:5]

Participants

5

Reactant 2

HCID 313Hydrochloric AcidHCID 867396452-Amino-2'-[alpha-(hydroxyimino)benzyl]-4'-nitro-acetanilide

Product 1

HCID 867396482-Amino-2'-[alpha-(hydroxyimino)benzyl]-4'-nitro-acetanilide hydrochloride

Reagents, catalysts & solvents 2

HCID 702EthanolSolventHCID 6344DichloromethaneSolvent

Procedure

Hydrogen chloride is conducted for 10 minutes into a solution of 2.7 g (8.59 mmol) of 2-amino-2'-[α-(hydroxyimino)benzyl]-4'-nitro-acetanilide in 150 ml of methylene chloride and 30 ml of ethanol. The solution is subsequently evaporated to dryness and the residue is dried at 60° overnight in vacuo. There is obtained 2-amino-2'-[α-(hydroxyimino)benzyl]-4'-nitro-acetanilide hydrochloride of melting point 150° (decomposition).

Workup

  1. customThe solution is subsequently evaporated to dryness
  2. customthe residue is dried at 60° overnight in vacuo

Sources & evidence

ORD record
ord-a0ddf31a356b41f3b2102d59c0ce943d
Source dataset
uspto-grants-1984_09
Patent number
US04472435

Linked notes

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