2-Methylquinoline → 4-Cyclohexyl-2-methylquinoline

HRID 2418811Notes

Reaction equation

HRID 2418811 reaction equation
Cc1ccc2ccccc2n1.O=C(O)C1CCCCC1>CS(C)=O.N.O.O=S(=O)(O)OOS(=O)(=O)O>Cc1cc(C2CCCCC2)c2ccccc2n1

Participants

6

Reactant 2

HCID 70602-MethylquinolineHCID 7413Cyclohexanecarboxylic acid

Product 1

HCID 133477574-Cyclohexyl-2-methylquinolineYield 78%

Reagents, catalysts & solvents 3

HCID 21864320CID 21864320ReagentHCID 679Dimethyl SulfoxideSolventHCID 962WaterSolvent

Conditions

Temperature
40 °C

Sources & evidence

ORD record
ord-52de714f0ca342bbb41f6b45117859e5
Source dataset
Minisci dataset from Roche

Reaction notes

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