Methyl iodide → HCID 12493310, compound

HRID 2419642

Reaction equation

HRID 2419642 reaction equation
[N:1]1[CH:2]=[CH:3][N:4]2[C:9]=1[CH:8]=[N:7][NH:6][C:5]2=[S:10].[Na].[CH3:12]I>C(O)C>[CH3:12][S:10][C:5]1[N:4]2[CH:3]=[CH:2][N:1]=[C:9]2[CH:8]=[N:7][N:6]=1

Participants

5

Reactant 3

HCID 6328Methyl iodideHCID 5360545SodiumHCID 12493308Imidazo[1,2-d]-as-triazine-5(6H)-thione

Product 1

HCID 12493310HCID 12493310, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent2×

Procedure

A 66.7 gm. portion of imidazo[1,2-d]-as-triazine-5(6H)-thione is added to 250 ml. of ethanol. A solution of 10.1 gm. of sodium reacted in 250 ml. of ethanol is added with swirling. A 27.7 ml. portion of methyl iodide is added slowly with swirling. The mixture is stored in a chillroom overnight, filtered and dried giving 56.5 gm. of the desired final product, m.p. 147°-149° C.

Workup

  1. customis stored in a chillroom overnight
  2. filtrationfiltered
  3. customdried
  4. customgiving 56.5 gm

Sources & evidence

ORD record
ord-ede1b65fcce7417db802e0a7b4ea8876
Source dataset
uspto-grants-1978_08
Patent number
US04107309

Linked notes

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