m-Chloroperbenzoic acid → HCID 20160906, compound
Reaction equation
[C:1]1([CH:7]([CH2:10][CH3:11])[C:8]#[N:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.ClC1C=CC=[C:15]([C:19]([O:21]O)=O)[CH:14]=1>>[CH2:10]([C:7]([C:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1)([CH2:14][CH:15]1[CH2:19][O:21]1)[C:8]#[N:9])[CH3:11]Participants
3
Procedure
The title compound was prepared by the methods described in Examples 2 and 3 except that 2-phenylbutyronitrile was used instead of methyl 2-phenylbutyrate and complete epoxidation required adding a second quantity of m-chloroperbenzoic acid. The resultant light-yellow oil was used in subsequent reactions without furher purification.
Workup
- customThe resultant light-yellow oil was used in subsequent reactions without furher purification
Sources & evidence
- ORD record
- ord-a41c669c11d44db29915a2c164770dfb
- Source dataset
- uspto-grants-1987_11
- Patent number
- US04707499
Reaction notes
Loading…