Sodium Hydroxide → HCID 178517083, compound

HRID 24784

Reaction equation

HRID 24784 reaction equation
C([N:4]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[C:6](=[C:13](OCC)[C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[C:5]1=[O:23])(=O)C.[O:24]1[CH2:29][CH2:28][N:27]([CH2:30][C:31]2[CH:37]=[CH:36][C:34]([NH2:35])=[CH:33][CH:32]=2)[CH2:26][CH2:25]1.[OH-].[Na+]>CN(C=O)C.CO>[O:24]1[CH2:25][CH2:26][N:27]([CH2:30][C:31]2[CH:37]=[CH:36][C:34]([NH:35]/[C:13](=[C:6]3\[C:5](=[O:23])[NH:4][C:12]4[C:7]\3=[CH:8][CH:9]=[CH:10][CH:11]=4)/[C:14]3[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=3)=[CH:33][CH:32]=2)[CH2:28][CH2:29]1

Participants

6

Reactant 3

HCID 14798Sodium HydroxideHCID 7768514-(Morpholinomethyl)anilineHCID 542378881-Acetyl-3-(1-ethoxy-1-phenylmethylidene}-2-indolinone

Product 1

HCID 178517083HCID 178517083, compound

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 6228DimethylformamideSolvent

Procedure

Prepared analogously to Example 1 from 1-acetyl-3-(1-ethoxy-1-phenyl-methylidene)-2-indolinone and 4-morpholinomethyl-aniline in DMF and subsequent treatment with sodium hydroxide solution in methanol.

Sources & evidence

ORD record
ord-8fca3dc42b8f4975aa9861844118c52c
Source dataset
uspto-grants-2005_02
Patent number
US06855710B2

Linked notes

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