2-Furancarbonyl chloride → N-[2-(3,4-methylenedioxyphenyl)ethyl]furan-2-carboxamide

HRID 248341

Reaction equation

HRID 248341 reaction equation
[O:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6](Cl)=[O:7].[CH2:9]1[O:20][C:19]2[CH:18]=[CH:17][C:13]([CH2:14][CH2:15][NH2:16])=[CH:12][C:11]=2[O:10]1>ClCCl.C(N(CC)CC)C>[CH2:9]1[O:20][C:19]2[CH:18]=[CH:17][C:13]([CH2:14][CH2:15][NH:16][C:6]([C:2]3[O:1][CH:5]=[CH:4][CH:3]=3)=[O:7])=[CH:12][C:11]=2[O:10]1

Participants

5

Reactant 2

HCID 682422-Furancarbonyl chlorideHCID 738741,3-Benzodioxole-5-ethanamine

Product 1

HCID 861822N-[2-(3,4-methylenedioxyphenyl)ethyl]furan-2-carboxamide

Reagents, catalysts & solvents 2

HCID 8471TriethylamineCatalystHCID 6344DichloromethaneSolvent

Procedure

N-[2-(3,4-methylenedioxyphenyl)ethyl]furan-2-carboxamide was prepared by condensation of 2-furoyl chloride and 3,4-methylenedioxyphenethylamine in dichloromethane with triethylamine as catalyst.

Sources & evidence

ORD record
ord-c36e56b9058745f0a375dfb3be1ffc73
Source dataset
uspto-grants-1993_05
Patent number
US05210088

Linked notes

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