Sodium Hydroxide → HCID 178490940, compound

HRID 24907

Reaction equation

HRID 24907 reaction equation
C([N:4]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[C:6](=[C:13](Cl)[C:14]2[CH:19]=[CH:18][C:17]([O:20][CH3:21])=[CH:16][CH:15]=2)[C:5]1=[O:23])(=O)C.[CH3:24][N:25]([CH2:27][C:28]1[CH:34]=[CH:33][C:31]([NH2:32])=[CH:30][CH:29]=1)[CH3:26].[OH-].[Na+]>CN(C=O)C.CO>[CH3:26][N:25]([CH2:27][C:28]1[CH:29]=[CH:30][C:31]([NH:32]/[C:13](=[C:6]2\[C:5](=[O:23])[NH:4][C:12]3[C:11]\2=[CH:10][CH:9]=[CH:8][CH:7]=3)/[C:14]2[CH:15]=[CH:16][C:17]([O:20][CH3:21])=[CH:18][CH:19]=2)=[CH:33][CH:34]=1)[CH3:24]

Participants

6

Reactant 3

HCID 14798Sodium HydroxideHCID 308051Benzenemethanamine, 4-amino-N,N-dimethyl-HCID 697411191-Acetyl-3-[1-chloro-1-(4-methoxyphenyl)-methylidene)-2-indolinone

Product 1

HCID 178490940HCID 178490940, compound

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 6228DimethylformamideSolvent

Procedure

Prepared analogously to Example 2 from 1-acetyl-3-[1-chloro-1-(4-methoxyphenyl)-methylidene)-2-indolinone and 4-dimethylaminomethyl-aniline in DMF and subsequent treatment with sodium hydroxide solution in methanol.

Sources & evidence

ORD record
ord-55d0e020b36341baab6101f3304e7bf7
Source dataset
uspto-grants-2005_02
Patent number
US06855710B2

Linked notes

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