1-Benzyl-4-piperidone → 1-Benzyl-4-piperidone oxime

HRID 249343

Reaction equation

HRID 249343 reaction equation

[CH2:1]([N:8]1[CH2:13][CH2:12][C:11](=O)[CH2:10][CH2:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Cl.[NH2:16][OH:17].C([O-])(=O)C.[Na+]>C(O)C>[CH2:1]([N:8]1[CH2:13][CH2:12][C:11](=[N:16][OH:17])[CH2:10][CH2:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

5

Reactant 3

HCID 192201-Benzyl-4-piperidone

HCID 443297Hydroxyamine hydrochloride

HCID 517045Sodium Acetate

Product 1

HCID 703651-Benzyl-4-piperidone oxime

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

18.9 g of 1-benzyl-4-oxopiperidine, 26.8 g of hydroxylamine hydrochloride, and 24.8 g of sodium acetate in 200 ml of ethanol are stirred for 8 hours.

Sources & evidence

ORD record: ord-1b8d7780c6414e0aad6c152685eab830
Source dataset: uspto-grants-1993_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05214055

Linked notes

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