HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Methylpyridine-2-carboxaldehyde → Bis-(3-methyl-pyridin-2-ylmethyl)-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Methylpyridine-2-carboxaldehyde | HCID 1501874 | — |
| Reactant | (3-Methylpyridin-2-yl)methanamine | HCID 1514370 | — |
| Reactant | Sodium triacetoxyborohydride | HCID 5049666 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | Bis-(3-methyl-pyridin-2-ylmethyl)-amine | HCID 45098010 | — |
Reaction Steps
Using General Procedure B: Reaction of 3-methyl-2-aminomethylpyridine and 3-methyl-2-pyridinecarboxaldehyde in CH2Cl2 with NaBH(OAc)3 gave bis-(3-methyl-pyridin-2-ylmethyl)-amine as a yellow oil. 1H NMR (CDCl3) δ 2.33 s, 6H), 4.06 (s, 4H), 7.08 (dd, 2H, J=9, 6 Hz), 7.42 (dd, 2H, J=9, 3 Hz), 8.41 (d, 2H, J=3 Hz).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07863293B2 |
| Source dataset | uspto-grants-2011_01 |
| ORD ID | ord-3c63327a6cd144c2a461ba8a471ee995 |
| Source note | uspto-grants-2011_01 |