2-Thiazolamine, 5-bromo- → 5-bromo-3-(2-methoxyethyl)thiazol-2(3H)-imine hydrobromide

Reaction equation

[NH2:1][C:2]1[S:3][C:4]([Br:7])=[CH:5][N:6]=1.[CH3:8][O:9][CH2:10][CH2:11]Br>>[BrH:7].[Br:7][C:4]1[S:3][C:2](=[NH:1])[N:6]([CH2:11][CH2:10][O:9][CH3:8])[CH:5]=1

Participants

Reactant 2

HCID 436002-Thiazolamine, 5-bromo-

HCID 809722-Bromoethyl methyl ether

Product 1

HCID 668599695-bromo-3-(2-methoxyethyl)thiazol-2(3H)-imine hydrobromide

Procedure

2-Amino-5-bromothiazole (Aldrich) and 2-bromoethyl methyl ether were processed as described in Example 2A to afford the title compound. MS (DCI/NH3) m/z 238 (M+H)+.

Sources & evidence

ORD record: ord-ed8a5c8eda6248a8aa521ef1491ec1bf
Source dataset: uspto-grants-2011_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07875639B2

Reaction notes

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