m-Chloroperbenzoic acid → 2,3-Dichloro-4,5bis-[(2-methoxyethoxy)-methoxy](1,2-epoxy) styrol

HRID 2580

Reaction equation

HRID 2580 reaction equation
[Cl:1][C:2]1[C:9]([Cl:10])=[C:8]([O:11][CH2:12][O:13][CH2:14][CH2:15][O:16][CH3:17])[C:7]([O:18][CH2:19][O:20][CH2:21][CH2:22][O:23][CH3:24])=[CH:6][C:3]=1[CH:4]=[CH2:5].ClC1C=CC=C(C(OO)=[O:33])C=1>C1CCCCC1.C(OCC)(=O)C>[Cl:1][C:2]12[O:33][C:3]1([CH:6]=[C:7]([O:18][CH2:19][O:20][CH2:21][CH2:22][O:23][CH3:24])[C:8]([O:11][CH2:12][O:13][CH2:14][CH2:15][O:16][CH3:17])=[C:9]2[Cl:10])[CH:4]=[CH2:5]

Participants

4

Reactant 2

HCID 70297m-Chloroperbenzoic acidHCID 183591652,3-Dichloro-4,5bis-[(2-methoxyethoxy)-methoxy]styrol

Product 1

HCID 183590672,3-Dichloro-4,5bis-[(2-methoxyethoxy)-methoxy](1,2-epoxy) styrolYield 99.6%

Reagents, catalysts & solvents 1

HCID 21867204Cyclohexane ethylacetateSolvent

Procedure

Using the procedure of Stage D of Example 40, 13.2 g of thee allylic alcohol of Step C and 10.3 g of m-chloro perbenzoic acid were reacted to obtain 13.7 g of the expected product with a Rf=0.25 (AcOEt-cyclohexane 6-4).

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-3ce42197cace4f5dad3160cf94f08e0c
Source dataset
uspto-grants-1998_03
Patent number
US05728828

Linked notes

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