N-(4-Chloro-2-methylphenyl)formamide → Formamide, N-(2-methylphenyl)-

HRID 258633

Reaction equation

HRID 258633 reaction equation
[CH:1]([NH:3][C:4]1[CH:9]=[CH:8][C:7](Cl)=[CH:6][C:5]=1[CH3:11])=[O:2]>CO>[CH:1]([NH:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[CH3:11])=[O:2]

Participants

3

Reactant 1

HCID 30815N-(4-Chloro-2-methylphenyl)formamide

Product 1

HCID 7202Formamide, N-(2-methylphenyl)-

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Splitting of the 2-formylamino-5-chlorotoluene, formed on chlorination of 2-formylaminotoluene, with methanol is performed at a temperature of between 20° and 60° C., preferably at between 25° and 30° C. The reaction duration is about 1 to 2 hours.

Sources & evidence

ORD record
ord-0e5282493e114da597907408c0830fb6
Source dataset
uspto-grants-1977_07
Patent number
US04034043

Linked notes

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