Butyric Acid → Heptafluorobutyric acid

Reaction equation

[F:1][C:2]([F:13])([C:9]([F:12])([F:11])[F:10])[C:3]([F:8])([F:7])[C:4]([F:6])=[O:5].C(O)(=[O:18])CCC.C(OC(=O)CCC)(=O)CCC>>[F:10][C:9]([F:12])([F:11])[C:2]([F:13])([F:1])[C:3]([F:8])([F:7])[C:4]([OH:18])=[O:5].[C:4]([F:6])(=[O:5])[CH2:3][CH2:2][CH3:9]

Participants

Reactant 3

HCID 264Butyric Acid

HCID 7798Butyric anhydride

HCID 67632Heptafluorobutyroyl fluoride

Product 2

HCID 9777Heptafluorobutyric acid

HCID 68035Butanoyl fluoride

Procedure

The following run illustrates the metathetical reaction of impure heptafluorobutyryl fluoride with butyric acid in the presence of butyric anhydride to give heptafluorobutyric acid and butyryl fluoride and the recovery of products from the reaction mixture by fractional distillation.

Sources & evidence

ORD record: ord-f0fd27ea775447efb4ba9fb622217ab9
Source dataset: uspto-grants-1977_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04038310

Reaction notes

Loading…