Dicyclohexylcarbodiimide → 2-Dimethylaminopyridine
Reaction equation
[CH3:1][C@H]1OC(=O)C2C(O)=CC(O)=C(Cl)C=2CC(=O)C=CC=C[C@H]2O[C@H]2C1.C(O)(=O)CCCCCCCCCCCCCC.[CH:43]1([N:49]=[C:50]=[N:51][CH:52]2[CH2:57][CH2:56][CH2:55]CC2)CCCCC1>O1CCCC1>[CH3:1][N:49]([C:50]1[CH:55]=[CH:56][CH:57]=[CH:52][N:51]=1)[CH3:43]Participants
5
Reactant 3
Product 1
Reagents, catalysts & solvents 1
Procedure
Following a procedure similar to that described in Example 12, but using 500 mg of radicicol, 830 mg of pentadecanoic acid, 15 ml of dry tetrahydrofuran, 707 mg of dicyclohexylcarbodiimide and a catalytic amount of dimethylaminopyridine, 782 mg of the title compound were obtained.
Sources & evidence
- ORD record
- ord-f3e95c19c8b144a99fa6d1e121193988
- Source dataset
- uspto-grants-1997_07
- Patent number
- US05650430
Reaction notes
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