Dicyclohexylcarbodiimide → 2-Dimethylaminopyridine

HRID 266192

Reaction equation

HRID 266192 reaction equation
[CH3:1][C@H]1OC(=O)C2C(O)=CC(O)=C(Cl)C=2CC(=O)C=CC=C[C@H]2O[C@H]2C1.OCCCCCCCCCCCC(O)=O.[CH:41]1([N:47]=[C:48]=[N:49][CH:50]2[CH2:55][CH2:54][CH2:53]CC2)CCCCC1>O1CCCC1>[CH3:1][N:47]([C:48]1[CH:53]=[CH:54][CH:55]=[CH:50][N:49]=1)[CH3:41]

Participants

5

Reactant 3

HCID 10868DicyclohexylcarbodiimideHCID 7903412-Hydroxydodecanoic AcidHCID 11268547CID 11268547

Product 1

HCID 218852-Dimethylaminopyridine

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

Following a procedure similar to that described in Example 12, but using 365 mg of radicicol, 1.8 g of 12-hydroxydodecanoic acid, 20 ml of dry tetrahydrofuran, 1 g of dicyclohexylcarbodiimide and a catalytic amount of dimethylaminopyridine, 485 mg of the title compound were obtained.

Sources & evidence

ORD record
ord-b49f3f8cb11947a5ab716e6cf5913649
Source dataset
uspto-grants-1997_07
Patent number
US05650430

Linked notes

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