Benzylamine → N-benzyladamantane-1-carboxamide

HRID 267876

Reaction equation

HRID 267876 reaction equation
[C:1]12([C:11](Cl)=[O:12])[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[CH2:2]1)[CH2:8]2.[CH2:14]([NH2:21])[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1>C(OCC)C>[CH2:14]([NH:21][C:11]([C:1]12[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[CH2:2]1)[CH2:8]2)=[O:12])[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1

Participants

4

Reactant 2

HCID 7504BenzylamineHCID 989151-Adamantanecarbonyl chloride

Product 1

HCID 3826889N-benzyladamantane-1-carboxamide

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

Dissolve 2.0 g. of (10 mmoles) of 1-adamantane carboxylic acid chloride in 20 ml. of ethyl ether and add to 3.0 ml. (28.0 mmoles) of benzylamine and repeat the process of Example 11 to obtain the product of this example, m.p. 170°-172°C.

Workup

  1. dissolutionDissolve 2.0 g
  2. customto obtain the product of this example, m.p. 170°-172°C.

Sources & evidence

ORD record
ord-370d15f0b8ad4bbdb3f3a0be1d3afd6a
Source dataset
uspto-grants-1976_03
Patent number
US03944675

Linked notes

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