Potassium Acetate → 3-Acetoxy-3-(2',4'-difluoro-4-biphenylyl)butan-1-ol
Reaction equation
Br[C:2]([C:7]1[CH:12]=[CH:11][C:10]([C:13]2[CH:18]=[CH:17][C:16]([F:19])=[CH:15][C:14]=2[F:20])=[CH:9][CH:8]=1)([CH3:6])[CH2:3][CH2:4][OH:5].FC1C=C(F)C=CC=1C1C=CC(C(C)CCO)=CC=1.[C:40]([O-:43])(=[O:42])[CH3:41].[K+]>>[C:40]([O:43][C:2]([C:7]1[CH:12]=[CH:11][C:10]([C:13]2[CH:18]=[CH:17][C:16]([F:19])=[CH:15][C:14]=2[F:20])=[CH:9][CH:8]=1)([CH3:6])[CH2:3][CH2:4][OH:5])(=[O:42])[CH3:41]Participants
4
Procedure
Analogously to Example 25 (a), 3-bromo-3-(2',4'-difluoro-4-biphenylyl)butan-1-ol, obtained by brominating 3-(2',4'-difluoro-4-biphenylyl)butan-1-ol, and potassium acetate are reacted to give 3-acetoxy-3-(2',4'-difluoro-4-biphenylyl)butan-1-ol.