Boron trifluoride etherate → HCID 178505646, compound
Reaction equation
[C:1]([C:3]1[CH:8]=[CH:7][CH:6]=[C:5]([F:9])[CH:4]=1)#[CH:2].[Li]CCCC.[C:15]([C:19](OCC)=O)([F:18])([F:17])[F:16].B(F)(F)F.O(CC)CC.[NH2:33][NH2:34]>C1COCC1.C1C=CC=CC=1>[F:9][C:5]1[CH:4]=[C:3]([C:1]2[NH:34][N:33]=[C:19]([C:15]([F:18])([F:17])[F:16])[CH:2]=2)[CH:8]=[CH:7][CH:6]=1Participants
8
Reactant 5
Product 1
Reagents, catalysts & solvents 2
Procedure
Following protocol H, 1-Ethynyl-3-fluoro-benzene was treated with n-BuLi, CF3CO2Et and BF3—OEt2 in THF. Reaction with hydrazine in benzene under similar reaction conditions yielded title compound.
Workup
- customunder similar reaction conditions
Sources & evidence
- ORD record
- ord-d8bdb191e76f452697277aaab9a78660
- Source dataset
- uspto-grants-2008_11
- Patent number
- US07449576B1
Reaction notes
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