Propargylamine → HCID 178457546, compound

HRID 27387

Reaction equation

[C:1]1([S:7]([C:10]([C:25]#[N:26])=[C:11](SC)[NH:12][CH2:13][CH2:14][S:15][CH2:16][C:17]2[NH:21][CH:20]=[N:19][C:18]=2[CH3:22])(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH2:27]([NH2:30])[C:28]#[CH:29]>>[C:1]1([S:7]([C:10]([C:25]#[N:26])=[C:11]([NH:30][CH2:27][C:28]#[CH:29])[NH:12][CH2:13][CH2:14][S:15][CH2:16][C:17]2[NH:21][CH:20]=[N:19][C:18]=2[CH3:22])(=[O:8])=[O:9])[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

Reactant 2

HCID 239041Propargylamine

HCID 178503876HCID 178503876, compound

Product 1

HCID 178457546HCID 178457546, compound

Procedure

The product of Step A is reacted with a four-fold excess of propargylamine according to the general procedure of Example 2, and the title product is produced.

Sources & evidence

ORD record: ord-c69af58343e5484282070668dfb95f59
Source dataset: uspto-grants-1980_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04221737

Linked notes

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