Cysteamine → 4-[(2-Aminoethyl)thiomethyl]-5-methyl-1,2,3-thiadiazole

Reaction equation

O[CH2:2][C:3]1[N:4]=[N:5][S:6][C:7]=1[CH3:8].[NH2:9][CH2:10][CH2:11][SH:12]>>[NH2:9][CH2:10][CH2:11][S:12][CH2:2][C:3]1[N:4]=[N:5][S:6][C:7]=1[CH3:8]

Participants

Reactant 2

HCID 6058Cysteamine

HCID 20147613(5-Methyl-1,2,3-thiadiazol-4-yl)methanol

Product 1

HCID 205675714-[(2-Aminoethyl)thiomethyl]-5-methyl-1,2,3-thiadiazole

Procedure

Reacting 4-hydroxymethyl-5-methyl-1,2,3-thiadiazole with cysteamine by the procedure of Example 1 gives 4-[(2-aminoethyl)thiomethyl]-5-methyl-1,2,3-thiadiazole.

Sources & evidence

ORD record: ord-2eb2e0a22a164cd3ab907159bd06e0be
Source dataset: uspto-grants-1980_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04221802

Reaction notes

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