Hydrogen Bromide → HCID 18316762, compound
Reaction equation
[NH2:1][C:2]1[CH:10]=[CH:9][C:5]([CH2:6][CH2:7]O)=[CH:4][CH:3]=1.[BrH:11]>>[BrH:11].[Br:11][CH2:7][CH2:6][C:5]1[CH:9]=[CH:10][C:2]([NH2:1])=[CH:3][CH:4]=1Participants
3
Procedure
To 4-aminophenethyl alcohol (25 g) was added 48% hydrobromic acid (250 ml), and the mixture was heated under reflux for 4 hours with stirring. After cooling, collection of the resulting precipitates by filtration gave 4-(2-bromoethyl)aniline hydrobromide (30.3 g).
Workup
- temperaturethe mixture was heated
- temperatureunder reflux for 4 hours
- temperatureAfter cooling
- customcollection of the resulting
- customprecipitates by filtration
Sources & evidence
- ORD record
- ord-027a6f8cf9374d9aa80d0ab52f08ffe0
- Source dataset
- uspto-grants-2002_03
- Patent number
- US06353025B1
Reaction notes
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