HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 3-chloro-4-hydroxyphenylacetate → 3-Chloro-4-(3'-chloro-4'-isobutoxybenzyloxy) phenylacetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 3-chloro-4-hydroxyphenylacetate | HCID 92625 | — |
| Reactant | 3-Chloro-4-isobutyoxybenzyl chloride | HCID 12347939 | — |
| Solvent | Methanol--water (1/1) | HCID 22242641 | — |
| Product | 3-Chloro-4-(3'-chloro-4'-isobutoxybenzyloxy) phenylacetic acid | HCID 53758658 | — |
Reaction Steps
The procedure of Example (1) (e) was repeated wherein 3-chloro-4-isobutyoxybenzyl chloride was reacted with methyl 3-chloro-4-hydroxyphenylacetate to yield 3-chloro-4-(3'-chloro-4'-isobutoxybenzyloxy) phenylacetic acid (52.4yield), m.p. 127.5°-129° C. (methanol-water).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04221919 |
| Source dataset | uspto-grants-1980_09 |
| ORD ID | ord-ed19a95cc9c14b48830e71430588f306 |
| Source note | uspto-grants-1980_09 |