HuagongsheHuagongshe Chemistry Print Report · For research reference only
P-Toluic Acid → (4-Methoxyphenyl)(4-methylphenyl)methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | P-Toluic Acid | HCID 7470 | — |
| Reactant | Anisole | HCID 7519 | — |
| Reactant | Ytterbium(3+) trifluoromethanesulfonate--water (1/3/1) | HCID 45075687 | — |
| Solvent | Chlorobenzene | HCID 7964 | — |
| Product | (4-Methoxyphenyl)(4-methylphenyl)methanone | HCID 32113 | 7% |
Reaction Steps
In like manner to Example 8, anisole and para-toluic acid were reacted together (4 hour reflux) in chlorobenzene in the presence of ytterbium (III) trifluoromethanesulfonate hydrate, to give crude 4-methoxy-4′-methylbenzophenone (0.15 g, 7% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06362375B1 |
| Source dataset | uspto-grants-2002_03 |
| ORD ID | ord-e9e79e661c064ff391d37c8d1f599ad8 |
| Source note | uspto-grants-2002_03 |