Sodium Ion → 2-(5-Chloro-2-fluorophenyl)-4-iodo-6,7-dihydrofuro[3,2-d]pyrimidine

Reaction equation

[Cl:1][c:2]1[c:3]2[c:4]([n:5][c:6](-[c:8]3[c:9]([F:15])[cH:10][cH:11][c:12]([Cl:14])[cH:13]3)[n:7]1)[CH2:16][CH2:17][O:18]2.[I-:20].[IH:19].[Na+:21].[OH2:22]>>[c:2]1([I:19])[c:3]2[c:4]([n:5][c:6](-[c:8]3[c:9]([F:15])[cH:10][cH:11][c:12]([Cl:14])[cH:13]3)[n:7]1)[CH2:16][CH2:17][O:18]2

Participants

Reactant 5

HCID 923Sodium Ion

HCID 962Water

HCID 24841Hydrogen iodide

HCID 30165Iodide Ion

HCID 211043394-Chloro-2-(5-chloro-2-fluorophenyl)-6,7-dihydrofuro[3,2-d]pyrimidine

Product 1

HCID 211043102-(5-Chloro-2-fluorophenyl)-4-iodo-6,7-dihydrofuro[3,2-d]pyrimidine

Sources & evidence

ORD record: ord-6852b2414832444a929ea51530f49175
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (8/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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