Potassium Cation → (3-Methoxy-benzyl)-[2-(3-thieno[2,3-d]isoxazol-3-yl-phenoxy)-ethyl]-amine

Reaction equation

[Br:1][CH2:2][CH2:3][O:4][c:5]1[cH:6][c:7](-[c:11]2[n:12][o:13][c:14]3[c:15]2[s:16][cH:17][cH:18]3)[cH:8][cH:9][cH:10]1.[C:19](=[O:20])([O-:21])[O-:22].[CH3:25][O:26][c:27]1[cH:28][c:29]([CH2:30][NH2:31])[cH:32][cH:33][cH:34]1.[CH3:35][C:36]#[N:37].[K+:23].[K+:24]>>[CH2:2]([CH2:3][O:4][c:5]1[cH:6][c:7](-[c:11]2[n:12][o:13][c:14]3[c:15]2[s:16][cH:17][cH:18]3)[cH:8][cH:9][cH:10]1)[NH:31][CH2:30][c:29]1[cH:28][c:27]([O:26][CH3:25])[cH:34][cH:33][cH:32]1

Participants

Reactant 5

HCID 813Potassium Cation2×

HCID 6342Acetonitrile

HCID 19660Carbonate Ion

HCID 211563-Methoxybenzylamine

HCID 219835823-[3-(2-Bromo-ethoxy)-phenyl]-thieno[2,3-d]isoxazole

Product 1

HCID 21983606(3-Methoxy-benzyl)-[2-(3-thieno[2,3-d]isoxazol-3-yl-phenoxy)-ethyl]-amine

Sources & evidence

ORD record: ord-a610ca0f33d042bcb1a301149c6a6c2b
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (8/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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