3-Bromothiophene → 1-(3,5-Dimethyl-4-isoxazolyl)-1-(3-thienyl)ethanol

HRID 2824

Reaction equation

[C:1]([C:4]1[C:5]([CH3:10])=[N:6][O:7][C:8]=1[CH3:9])(=[O:3])[CH3:2].Br[C:12]1[CH:16]=[CH:15][S:14][CH:13]=1>>[CH3:10][C:5]1[C:4]([C:1]([C:12]2[CH:16]=[CH:15][S:14][CH:13]=2)([OH:3])[CH3:2])=[C:8]([CH3:9])[O:7][N:6]=1

Participants

Reactant 2

HCID 133833-Bromothiophene

HCID 127203171-(3,5-Dimethylisoxazol-4-yl)ethanone

Product 1

HCID 189362861-(3,5-Dimethyl-4-isoxazolyl)-1-(3-thienyl)ethanol

Procedure

The title compound was prepared following the general method of Example 4 but starting with 4-acetyl-3,5-dimethylisoxazole and 3-bromothiophene.

Sources & evidence

ORD record: ord-9af96c4c69f344379ebe313338e1ebf0
Source dataset: uspto-grants-1998_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05731335

Linked notes

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