Toluene → 4-Cyclopropyl-2-fluoro-1-nitrobenzene

HRID 282489

Reaction equation

HRID 282489 reaction equation
[C:25](=[O:26])([O-:27])[O-:28].[CH3:31][c:32]1[cH:33][cH:34][cH:35][cH:36][cH:37]1.[CH:19]1([B:22]([OH:23])[OH:24])[CH2:20][CH2:21]1.[Cs+:29].[Cs+:30].[F:1][c:2]1[cH:3][c:4]([O:11][S:12]([C:13]([F:14])([F:15])[F:16])(=[O:17])=[O:18])[cH:5][cH:6][c:7]1[N+:8](=[O:9])[O-:10]>>[F:1][c:2]1[cH:3][c:4]([CH:19]2[CH2:20][CH2:21]2)[cH:5][cH:6][c:7]1[N+:8](=[O:9])[O-:10]

Participants

6

Reactant 5

HCID 1140TolueneHCID 19660Carbonate IonHCID 104967Cesium cation2×HCID 2760897Cyclopropylboronic acidHCID 219987353-Fluoro-4-nitrophenyl trifluoromethanesulfonate

Product 1

HCID 574239144-Cyclopropyl-2-fluoro-1-nitrobenzene

Sources & evidence

ORD record
ord-1934fc69b7484613aa59116cbf455b3d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Linked notes

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