1,2-Dichloroethane → N-((2-chloro-4-morpholinothieno[2,3-d]pyrimidin-6-yl)methyl)-N,1-dimethylpiperidin-4-amine

HRID 284956

Reaction equation

HRID 284956 reaction equation
[C:28]([OH:29])(=[O:30])[CH3:31].[CH3:19][NH:20][CH:21]1[CH2:22][CH2:23][N:24]([CH3:27])[CH2:25][CH2:26]1.[Cl:1][c:2]1[n:3][c:4]([N:13]2[CH2:14][CH2:15][O:16][CH2:17][CH2:18]2)[c:5]2[c:6]([n:7]1)[s:8][c:9]([CH:11]=[O:12])[cH:10]2.[Cl:32][CH2:33][CH2:34][Cl:35]>>[Cl:1][c:2]1[n:3][c:4]([N:13]2[CH2:14][CH2:15][O:16][CH2:17][CH2:18]2)[c:5]2[c:6]([n:7]1)[s:8][c:9]([CH2:11][N:20]([CH3:19])[CH:21]1[CH2:22][CH2:23][N:24]([CH3:27])[CH2:25][CH2:26]1)[cH:10]2

Participants

5

Reactant 4

HCID 111,2-DichloroethaneHCID 176Acetic AcidHCID 5663231-Methyl-4-(methylamino)piperidineHCID 568338442-Chloro-4-morpholinothieno[2,3-d]pyrimidine-6-carbaldehyde

Product 1

HCID 86623517N-((2-chloro-4-morpholinothieno[2,3-d]pyrimidin-6-yl)methyl)-N,1-dimethylpiperidin-4-amine

Sources & evidence

ORD record
ord-ab225c0126d54611b0880f26bb81d5f9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Linked notes

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