Sodium Chloride → N-[1-(4-aminophenyl)ethylidene]hydroxylamine

To a mixture of 1-(4-amino-phenyl)-ethanone (2.75 g, 20.3 mmol) and hydroxylamine hydrochloride salt (2.1 g, 30.5 mmol) in ethanol (200 ml) was added sodium hydroxide (4.1 g, 101.7 mmol) in water (50 ml). After stirring for 18 hours, the mixture was treated with saturated aqueous sodium chloride solution (100 ml) and extracted with dichloromethane (200 ml). The organic extract was concentrated under reduced pressure to afford 1-(4-amino-phenyl)-ethanone-oxime (30% yield).

1. extractionextracted with dichloromethane (200 ml)
2. extractionThe organic extract
3. concentrationwas concentrated under reduced pressure

ORD record

ord-4d7aca234a664cbe99991eb96404e5e8

Source dataset

uspto-grants-2008_09

DOI

10.6084/m9.figshare.5104873.v1

Patent number

US07419984B2