Hydrochloric Acid → 6'-bromo-4,4-difluorospiro[cyclohexane-1,2'-inden]-1'(3'H)-imine

Reaction equation

[Br:2][c:3]1[cH:4][c:5]2[c:16]([cH:17][cH:18]1)[CH2:15][C:7]1([C:6]2=[N:19][S:20]([C:21]([CH3:22])([CH3:23])[CH3:24])=[O:25])[CH2:8][CH2:9][C:10]([F:13])([F:14])[CH2:11][CH2:12]1.[CH2:31]1[O:32][CH2:33][CH2:34][O:35][CH2:36]1.[CH3:26][CH2:27][O:28][CH2:29][CH3:30].[ClH:1]>>[Br:2][c:3]1[cH:4][c:5]2[c:16]([cH:17][cH:18]1)[CH2:15][C:7]1([C:6]2=[NH:19])[CH2:8][CH2:9][C:10]([F:13])([F:14])[CH2:11][CH2:12]1

Participants

Reactant 4

HCID 313Hydrochloric Acid

HCID 3283Diethyl Ether

HCID 312751,4-Dioxane

HCID 67979525N-(5'-Bromo-4,4-difluorospiro[cyclohexane-1,2'-indene]-3'(1'H)-ylidene)-2-methylpropane-2-sulfinamide

Product 1

HCID 679795136'-bromo-4,4-difluorospiro[cyclohexane-1,2'-inden]-1'(3'H)-imine

Sources & evidence

ORD record: ord-ea2d903fb1bc4612b9fd3fb60d288851
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (8/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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