Tetrahydrofuran → 3-[2-(4-Fluorophenyl)acetyl]-4-propan-2-yl-1,3-oxazolidin-2-one

HRID 286722

Reaction equation

HRID 286722 reaction equation
[CH2:26]1[O:27][CH2:28][CH2:29][CH2:30]1.[CH3:10][CH2:11][CH2:12][CH2:13][Li:14].[CH:1]([CH3:2])([CH3:3])[CH:4]1[NH:5][C:6](=[O:9])[O:7][CH2:8]1.[F:15][c:16]1[cH:17][cH:18][c:19]([CH2:22][C:23](=[O:24])[Cl:25])[cH:20][cH:21]1>>[CH:1]([CH3:2])([CH3:3])[CH:4]1[N:5]([C:23]([CH2:22][c:19]2[cH:18][cH:17][c:16]([F:15])[cH:21][cH:20]2)=[O:24])[C:6](=[O:9])[O:7][CH2:8]1

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 5193532-Oxazolidinone, 4-(1-methylethyl)-HCID 37449884-Fluorophenylacetyl chlorideHCID 178418339Butyllithium

Product 1

HCID 167561823-[2-(4-Fluorophenyl)acetyl]-4-propan-2-yl-1,3-oxazolidin-2-one

Sources & evidence

ORD record
ord-4791b8fe5e9a462da6d706c6be93d72b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Linked notes

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