Sodium ion → 7-bromo-5-chloro-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-indole-3-carbonitrile

HRID 289904

Reaction equation

HRID 289904 reaction equation
[Br:3][c:4]1[cH:5][c:6]([Cl:15])[cH:7][c:8]2[c:9]([C:13]#[N:14])[cH:10][nH:11][c:12]12.[CH2:25]1[O:26][CH2:27][CH2:28][CH2:29]1.[CH3:16][Si:17]([CH2:18][CH2:19][O:20][CH2:21][Cl:22])([CH3:23])[CH3:24].[H-:1].[Na+:2]>>[Br:3][c:4]1[cH:5][c:6]([Cl:15])[cH:7][c:8]2[c:9]([C:13]#[N:14])[cH:10][n:11]([CH2:21][O:20][CH2:19][CH2:18][Si:17]([CH3:16])([CH3:23])[CH3:24])[c:12]12

Participants

6

Reactant 5

HCID 923Sodium ionHCID 8028TetrahydrofuranHCID 166653HydrideHCID 27242712-Chloromethyl 2-(trimethylsilyl)ethyl etherHCID 575462207-bromo-5-chloro-1H-indole-3-carbonitrile

Product 1

HCID 575460027-bromo-5-chloro-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-indole-3-carbonitrile

Sources & evidence

ORD record
ord-e5a7e37f07204a5ea21738cd332cb942
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Linked notes

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