Phosphorus oxychloride → 4-Bromo-6-(4-methyl-1-piperazinyl)-9-methyl-1,2-dihydrobenzo[b]-pyrrolo [3,2,1-jk][1,4]benzodiazepine

HRID 293302

Reaction equation

HRID 293302 reaction equation
[Br:1][c:2]1[cH:3][c:4]2[c:8]([cH:9][cH:10]1)[N:7]([c:11]1[c:12]([NH:18][C:19](=[O:20])[N:21]3[CH2:22][CH2:23][N:24]([CH3:27])[CH2:25][CH2:26]3)[cH:13][c:14]([CH3:17])[cH:15][cH:16]1)[CH2:6][CH2:5]2.[P:28]([Cl:29])([Cl:30])([Cl:31])=[O:32]>>[Br:1][c:2]1[cH:3][c:4]2[c:8]3[c:9]([cH:10]1)[C:19]([N:21]1[CH2:22][CH2:23][N:24]([CH3:27])[CH2:25][CH2:26]1)=[N:18][c:12]1[c:11]([cH:16][cH:15][c:14]([CH3:17])[cH:13]1)[N:7]3[CH2:6][CH2:5]2

Participants

3

Reactant 2

HCID 24813Phosphorus oxychlorideHCID 13823367N-[2-(5-bromo-1-indolinyl)-5-methylphenyl]-4-methyl-1-piperazinecarboxamide

Product 1

HCID 138233144-Bromo-6-(4-methyl-1-piperazinyl)-9-methyl-1,2-dihydrobenzo[b]-pyrrolo [3,2,1-jk][1,4]benzodiazepine

Sources & evidence

ORD record
ord-693506122330450b96b5763fa231447a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Linked notes

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