Acetic Acid → 1-Cyclopropyl-6,7-difluoro-8-hydroxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

HRID 295547

Reaction equation

[BrH:22].[C:23]([OH:24])(=[O:25])[CH3:26].[CH:1]1([n:4]2[cH:5][c:6]([C:19](=[O:20])[OH:21])[c:7](=[O:18])[c:8]3[cH:9][c:10]([F:17])[c:11]([F:16])[c:12]([O:14][CH3:15])[c:13]23)[CH2:2][CH2:3]1.[OH2:27]>>[CH:1]1([n:4]2[cH:5][c:6]([C:19](=[O:20])[OH:21])[c:7](=[O:18])[c:8]3[cH:9][c:10]([F:17])[c:11]([F:16])[c:12]([OH:14])[c:13]23)[CH2:2][CH2:3]1

Participants

Reactant 4

HCID 176Acetic Acid

HCID 260Hydrogen Bromide

HCID 962Water

HCID 70194651-Cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid

Product 1

HCID 116807371-Cyclopropyl-6,7-difluoro-8-hydroxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

Sources & evidence

ORD record: ord-48b6958b6cc540b695a1f951d9c40068
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (8/10)
DOI: 10.1039/C8SC04228D

Linked notes

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