Dimethylformamide → N-[4-chloro-2-(oxiran-2-ylmethoxy)phenyl]acetamide

HRID 297042

Reaction equation

HRID 297042 reaction equation
[C:30](=[O:31])([O-:32])[O-:33].[Cl:18][c:19]1[cH:20][c:21]([OH:29])[c:22]([NH:25][C:26]([CH3:27])=[O:28])[cH:23][cH:24]1.[Cs+:34].[Cs+:35].[O:1]1[CH:2]([CH2:4][O:5][S:6]([c:7]2[cH:8][cH:9][cH:10][c:11]([N+:12]([O-:13])=[O:14])[cH:15]2)(=[O:16])=[O:17])[CH2:3]1.[O:36]=[CH:37][N:38]([CH3:39])[CH3:40]>>[O:1]1[CH:2]([CH2:4][O:29][c:21]2[cH:20][c:19]([Cl:18])[cH:24][cH:23][c:22]2[NH:25][C:26]([CH3:27])=[O:28])[CH2:3]1

Participants

6

Reactant 5

HCID 6228DimethylformamideHCID 19660Carbonate IonHCID 104967Cesium cation2×HCID 177739N-(4-Chloro-2-hydroxyphenyl)acetamideHCID 286836(Oxiran-2-yl)methyl 3-nitrobenzene-1-sulfonate

Product 1

HCID 85915343N-[4-chloro-2-(oxiran-2-ylmethoxy)phenyl]acetamide

Sources & evidence

ORD record
ord-60307438286f420dba5f757c3c0566f0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Linked notes

Loading…