Dichloromethane → 1-(2-Methoxyphenyl)sulfonyl-2-oxo-3-[2-oxo-1-phenyl-2-[3-(4-propylpiperazin-1-yl)pyrrolidin-1-yl]ethyl]benzimidazole-5-carbonitrile

HRID 299130

Reaction equation

HRID 299130 reaction equation
[CH3:36][O:37][c:38]1[c:39]([S:44](=[O:45])(=[O:46])[Cl:47])[cH:40][cH:41][cH:42][cH:43]1.[CH3:48][N:49]([c:50]1[cH:51][cH:52][n:53][cH:54][cH:55]1)[CH3:56].[Cl:57][CH2:58][Cl:59].[O:1]=[c:2]1[n:3]([CH:13]([C:14]([N:15]2[CH2:16][CH:17]([N:20]3[CH2:21][CH2:22][N:23]([CH2:26][CH2:27][CH3:28])[CH2:24][CH2:25]3)[CH2:18][CH2:19]2)=[O:29])[c:30]2[cH:31][cH:32][cH:33][cH:34][cH:35]2)[c:4]2[c:5]([nH:6]1)[cH:7][cH:8][c:9]([C:11]#[N:12])[cH:10]2>>[O:1]=[c:2]1[n:3]([CH:13]([C:14]([N:15]2[CH2:16][CH:17]([N:20]3[CH2:21][CH2:22][N:23]([CH2:26][CH2:27][CH3:28])[CH2:24][CH2:25]3)[CH2:18][CH2:19]2)=[O:29])[c:30]2[cH:31][cH:32][cH:33][cH:34][cH:35]2)[c:4]2[c:5]([n:6]1[S:44]([c:39]1[c:38]([O:37][CH3:36])[cH:43][cH:42][cH:41][cH:40]1)(=[O:45])=[O:46])[cH:7][cH:8][c:9]([C:11]#[N:12])[cH:10]2

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 142844-(Dimethylamino)pyridineHCID 37458512-Methoxybenzenesulfonyl ChlorideHCID 667547972-oxo-3-[2-oxo-1-phenyl-2-[3-(4-propylpiperazin-1-yl)pyrrolidin-1-yl]ethyl]-1H-benzimidazole-5-carbonitrile

Product 1

HCID 667554831-(2-Methoxyphenyl)sulfonyl-2-oxo-3-[2-oxo-1-phenyl-2-[3-(4-propylpiperazin-1-yl)pyrrolidin-1-yl]ethyl]benzimidazole-5-carbonitrile

Sources & evidence

ORD record
ord-6a751850ee694c338dd97a41650b4e80
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Linked notes

Loading…